Engineering Questions with Answers - Multiple Choice Questions

MCQs on Recombination

1 - Question

. Rearrangement of DNA that involves the breakage and reunion of DNA is called___________
a) Replication
b) Recombination
c) Translation
d) Transcription

View Answer

Answer: b
Explanation: Recombination is the process of rearrangement of DNA of breakage and reunion and it can change the genomic configuration.




2 - Question

Recombination is responsible for crossing-over during meiosis of eukaryotic cells.
a) True
b) False

View Answer

Answer: a
Explanation: Recombination was first recognized as the process which is responsible for crossing over in the meiosis. It is a large scale rearrangement of DNA molecules.




3 - Question

Which of the following is NOT true about homologous recombination?
a) Exchange of homologous segments
b) Exchange takes place between two homologous DNA molecules
c) It is also termed as general recombination
d) It involves a direct exchange of sequences of DNA

View Answer

Answer: d
Explanation: Homologous recombination involves a reciprocal exchange of sequences of DNA.




4 - Question

Which of the following is site specific recombination?
a) Modification
b) Transposition
c) Holiday junction
d) Retrotransposons

View Answer

Answer:b
Explanation: Transposition is the process of recombination, which allows one DNA sequence to inserted in another without taking care of sequence homology.




5 - Question

Who proposed holiday model for homologous recombination?
a) Gobind Khurana
b) Louis Pasteur
c) Robin Holiday
d) Niels Bohr

View Answer

Answer: c
Explanation: Robin Holiday in 1964, proposed an appealing scheme for recombination called holiday model or hetroduplex model.




6 - Question

Which of the following is NOT a recombination system?
a) RecBCD
b) RecE
c) RecF
d) DnaF

View Answer

Answer: d
Explanation: Homologous recombination was first described in bacterial systems. The three different recombination systems are RecF, RecE, and RecBCD.




7 - Question

Name the phenomenon of allele replacement during recombination and DNA repair?
a) Replication
b) Mutation
c) Transversion
d) Gene conversion

View Answer

Answer: d
Explanation: Gene conversion is the phenomenon of changing allele forms during recombination and DNA repair.




8 - Question

Name the protein, which is involved in homologous recombination in E.coli?
a) Topoisomerase
b) Gyrase
c) Helicase
d) RecBCD enzyme

View Answer

Answer: d
Explanation: The three different recombination systems are RecF, RecE, and RecBCD. RecBCD is known as Exonuclease V and it has both helicase and nuclease activity.

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