Engineering Questions with Answers - Multiple Choice Questions

MCQs on Chemical Basis of Life – Chaperones

1 - Question

What are molecular chaperones?
a) Enzymes
b) Cell mass
c) Tumor
d) Helper proteins

View Answer

Answer: d
Explanation: Molecular chaperones are helper proteins that help unfolded or misfolded polypeptide chains to assume a certain folded state. The role of these proteins is to prevent the proteins from non-selectively interacting with other components in the cell.

2 - Question

Chaperones bind to which type of amino acid residues in the protein?
a) Charged
b) Uncharged
c) Hydrophobic
d) Hydrophilic

View Answer

Answer: c
Explanation: Chaperons are helper proteins that binds to hydrophobic amino acid residues that are part of the core of the folded protein. In the denatured state the core amino acid residues are exposed which is identified. Once bound the polypeptide molecule is folded like a hairpin into its tertiary state.

3 - Question

. Which of the following molecules bind to nascent polypeptides synthesized on the ribosomes?
a) Chaperonins
b) Hsp70
c) Hsp72
d) Hsp

View Answer

Answer: c
Explanation: Hsp70 is a class of molecular chaperones that bind to nascent proteins being synthesized on ribosomes. Hsp70 chaperones prevent the newly synthesized proteins from binding to other proteins in the cytosol which could lead to misfolding or aggregation.

4 - Question

TriC is a _____________
a) hsp70
b) chaperonin
c) organelle
d) enzyme

View Answer

Answer: b
Explanation: TriC is a chaperonin that helps stabilize long polypeptides. It contains chambers in which peptides can reside without any interference from the external environment.

5 - Question

Heat-shock response was first observed in which organism?
a) C. elegans
b) Drosophila
c) Arabidopsis
d) Bacteria

View Answer

Answer: b
Explanation: Heat shock response on the form of production of heat shock proteins was first observed in Drosophila. In 1962, an Italian biologist was studying the development of Drosophila when it was observed that increasing the temperature, at which larvae grow new heat shock proteins appear on the chromosome.

6 - Question

Rubisco is a ________________
a) nucleic acid
b) protein
c) carbohydrate
d) fiber

View Answer

Answer: b
Explanation: Rubisco is a protein found in chloroplasts of plant cells, it catalyzes the reaction in which carbon dioxide taken up from the atmosphere is covalently linked to organic molecules.

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